Friday, September 13, 2019

Biologics PRODUCTION AND MARKET Essay Example | Topics and Well Written Essays - 1000 words

Biologics PRODUCTION AND MARKET - Essay Example epresent a significant proportion of the pharmaceutical market according to Aagaard, Purdy, and Philpott (2010) who cite that in 2007 American consumers reportedly spent approximately $40 billion on biologics constituting about 13.9 percent of the overall money spent on prescription drugs. The statistics further show an increase in the use and prescription of biologics in the coming years. Visiongain, an international company, predicted that the market share of the biologics would immensely increase over these years. According to the statistical data, these biologics will reach an estimated 178.4 billion by 2017. It was also found that biologics formed 15% of the pharmaceutical market in the year 2012 (Visiongain, 2013). Another report put forward by Allied Market Research also found out that the market of biologics would increase drastically over the years to come. According to Allied Market Research, it is estimated that the share would increase from a total of $1.3 billion in 2013 to $35 billion by the year 2020. This clearly shows that the demand for biologics will keep on increasing as time is passing by (Market Watch, 2015). According to the forecasts, this has increased from $46 billion to $169 billion in the year of 2012 and is further expected to increase to $221 billion by 2017. Following is the graphical data which shows the forecast of biologics between th e years of 2004 till 2017. However despite the success of biologics in the field of healthcare, there has been much debate regarding the approval of and patenting of the relevant technology. Biologics go through a fast track approval process which greatly speeds the process. Much of the criticism pertaining to fast track approval procedure for biologics focuses on safety concerns which are ignored during the fast process. According to the FDA (2011), the fast track procedure is to allow for speedy approval of biologics for treatment of life-threatening diseases and hence is required due to necessity.

Thursday, September 12, 2019

Public Relations Campaigns Article Example | Topics and Well Written Essays - 250 words

Public Relations Campaigns - Article Example They are the key people because even though the impact of the project will be felt by the whole city, those people will receive the first hand impact since they have to relocate their homes and business, suffer losses among other impacts most of which are negative. The theme of this project is â€Å"public relations campaign for the city’s development† and it aims at garnering public support from the city dwellers on the upcoming development project. The message for the above mentioned group is to persuade them to look at the positive impact the development project will have in not only their lives but also the lives of their children in future once this whole project is finished. More business opportunities will be created when tourists start to visit the city in order to view the project or participate in cultural festivals and shows that will be hosted in the completed building that wants to be developed now. There are several ways to reach the public: to have forums with them in their business areas or home locations, door-to-door campaign and especially for those who live in that area that the development project is to come up, media intervention like announcements, discussion programs, posters, and finally meetings with the city residents in halls among other ways (Gregory,

Wednesday, September 11, 2019

Communications Paper on Media Essay Example | Topics and Well Written Essays - 1000 words

Communications Paper on Media - Essay Example Newspapers also serve a surveillance purpose as they inform about what is going on. Through media, I also satisfy my social and psychological needs. This means media is a powerful tool for transmission of cultures and norms. I am able to be informed and learn about various norms and how I am expected to behave, as well. For instance watching television programs about other cultures makes me aware about them. I am also able to learn about their norms whether it is through print or visual media. Media is also utilized as an advertising tool. Media covers a wide audience making it a powerful tool for advertising and marketing. It is also used to influence the thoughts and needs of the society. Such form of media can be through propaganda whereby information is put out by an organization to promote a particular policy. From all these, the media serve as a gratification tool to the larger society since its survival is on the basis of satisfying the needs of a society (Gibson). 2. Costs sp ent on media Various media exist in our daily lives; therefore, costs are incurred when it comes to accessing media. To access the print media I have to purchase newspapers and magazines some of which are updated daily; thus, it makes sense to acquire them each new day. Print media are extremely important, but more expensive to access; thus, I spend more on it. For instance, to access academic materials, I have to purchase books, which are not easily available via the internet resource. Media is also important because communication and entertainment are a normal part of the day-to-day activities. Visual media are characterized by television and the internet. Costs are incurred in electricity bills and payment of internet subscription fees. When all costs are summed up it can be determined that a lot of money is directed on media in a given month. This can also be summarized by the fact that media consumptions occurs every day. 3. Description of a day without media A day without medi a is quite different since media had evolved to be a habit in my lifestyle. My first instinct in the morning was to check my phone, but I had to ignore the urge. Without media, I would not be in constant touch with others; thus I would not be able to know where I am needed and by whom. I will also find it hard to be informed about new developments around me. Because it felt like an addiction, I could not last a whole day without thinking about what I am missing. For instance, I could not be in contact with my friends and colleagues; thus, I would not be informed about how they are doing or if they have any information related to me. I would also tend to be scared at times because I was not certain about what I am supposed to do during the day. I could not read posters and information posted on notice boards; thus, I was not comfortable. Generally, I felt like I was in my own world since I was not able to access any new information that might influence me. Therefore, from morning to evening I was only making an appearance, but never really involved in anything constructive. By dawn, I felt I had lost a lot of opportunities. 4. What was learned From the experience on that day, I was able to learn and appreciate just how important media is to my daily activities. If I was given such a test, again it would be hard to try it because on that single day, I had missed on a lot. The urge to get information was quite big and I learned that I was

Tuesday, September 10, 2019

How does my school compare with other schools in the U.S Essay

How does my school compare with other schools in the U.S - Essay Example In some respects there are some schools like the universities who have access to technology but there are many websites that they block. According to Hermida the ones that are blocked have to do with sexually explicit content, womens history, religious sites, drugs and pop culture (Hermida, 2003). These sites are basically blocked because the government does not want Saudi people getting ideas that may mean they go against their religion. This is very different from U.S. education because in the U.S. there are some things that are blocked by education like pornography sites but for the most part students have access to many things that will enhance their learning. According to the Saudi government the reason why these sites are blocked is because they want to preserve their customs and their religion. When they block a site it makes sure that their people will remain loyal to their religion. This is very important on Saudi Arabia (Hermida). There is a question about the technology situation. It is one thing to have technology but if it is censored it seems that this defeats the purpose. In the U.S. students can find out about people and situations that are different from their own. In Saudi Arabia they cannot. This may mean that the Saudi children do not receive the same type of education as those in the U.S. because they lack the flexibility of the Internet. When someone takes an engineering course or something to do with business they are able to use the full technology in that area. This means that it will be offered to men more than it will be offered to women. It seems that the Saudis know that men will need to have a better understanding of the Internet because they will be doing business on a global basis. It is important to keep in mind that the goal of education in Saudi Arabia is very different than the goal of the U.S. In the U.S. people go for education because they want to advance their career or

Monday, September 9, 2019

Brand positioning and focus Research Paper Example | Topics and Well Written Essays - 1250 words

Brand positioning and focus - Research Paper Example This research is intended to develop the sound understanding of the impact of the branding on the lives of individuals, especially their buying decisions. Moreover, we also aim to identify the best practices of branding in contemporary era. In past era, branding was considered to be what it is considered now. Few years back, brand used to be defined as "the name,associated with one or more items in the product line, that is used to identify the source of character of the item(s)" (Kotler 2000, p. 396) Another definition that was given by Keller (2003) depicts the same thought. He defines brands as "technically speaking, the n, whenever a marketer creates a new name, logo, or symbol for a new product, he or she has created a brand" (p. 3)" However, over the period of time, it was realized that branding has far wider scope than this. Realizing this, people started to explore more avenues into it. "For a long time, the brand has been treated in an off-hand fashion as a part of the product" (Urde 1999, p. 119). With the changing time, the needs and demands of the businesses were changing too. "The challenge today is to create a strong and distinctive image" (Kohli and Thakor 1997, p. 208). This definition shows that the scope of branding has been broadened and besides providing identity to the product, it is also responsible for conveying to customers that brand message associated to that brand through the process of branding. The modern concept of branding is associated to a number of other related concepts. In order to make the brand successful and the high impact brand, one of the most essential part is its positioning. It is well known phrase in the marketing circles that those brands which are top in terms of customer recall are really the leaders. Thus, brand positioning means that a brand should be presented as a response to some customer need, in order to make it successful. For example, if a company sells the cars. The brand manager of that particular car should see that what particular needs that car is going to fulfill for the customers and present the product as simply not the product, rather, the solution to that need of the consumer. Keeping in view the customer needs is simply one factor, others may include competitor's move, emerging trends and so on and so forth. Besides, other factors of success include, targeted marketing, efficient segmenting and focused advertising and public relations . Targeting marketing and focus advertising are essential because, we can't market our product to everyone. There is a cost to it. Every second that runs an ad on any channels, it costs a handsome some of money to the producer and this price is ultimately shifted to the customer. If lesser people Brand purchase that product, higher contribution from each purchaser is required. In today's world where there is cutting edge competition, one

Sunday, September 8, 2019

Japanese Culture Essay Example | Topics and Well Written Essays - 750 words

Japanese Culture - Essay Example Allied Forces occupied Post-War Japan (1945-1952) and the General Douglas MacArthur of the United States ruled there. This order and these changes have exerted a significant impact on Japanese culture. A democratic world order has seized Japan’s military rule of the world. The war was devastating and many territories of Japan had to be subjected to the newly existent order. There was a constant intention of the Japanese nation to gain superiority in some spheres of their activities. For example, Japanese engineers came to the US companies made systematic attempts to improve different production modes. At this point technological background of popular culture development can be found. Thesis: Therefore modern culture of Japan is developed with respect to military context, changes of post-war period, social oppression and innovative social order of the society. Japan after war After war Japan intended to find new ways of profits gaining. In the result of their practices, Japan t urned into a consumer-oriented producer. Electronics was one of the most important concerns for Japan. Moreover, a great attention was paid to innovative automobile design (which was borrowed from the principles of Japanese aesthetics). After 1980s Japan gained reputation of the largest creditor nation on earth, and America turned into the largest debtor. Japanese popular culture has been spread all over the globe after rapid growth of industrialization and information bum. The Asian world wanted to reach pace of Japan development1. Post-war period of the country's development was marked by unique and vibrant culture, which is often associated with innovations in China and Korea and the rest of the Asian world. It cannot be denied that "markers of loss" after the war have been gradually disappearing from the Japanese culture. Culture development from the 1950s to the mid-1960s it was difficult for Japanese people to find their identities. They were puzzled by numerous losses after t he war. For example, we can refer to the drama and film,  Kimino na wa, the film  Gojira  (Godzilla), and the professional wrestler Rikidozan, where specific features and cultural templates of Japanese culture can be identified2. In the chapter "From the Anti-Security Treaty Movement to the Tokyo Olympics: Transforming the Body, the Metropolis, and Memory" the restructuring images of the resurfaced memories of the past are discussed. It can be claimed for sure that the memories should have been transformed and cleansed till 1964, the year of Tokyo Olympic. Tokyo has been changed into a clean and successful city. The Japanese volleyball team gain victory against the former Soviet team and this team signified the path of Japan's progress and a gradual restoration. Thus, there is a consequential transformation of the Japanese culture. The central principle of cultural development of Japan after war was a peaceful strategy3. The eternal peace was very important issue for the Japan ese culture. A rejection of military service in Japan has left a significant impact on the country's development. Igarashi integrates post-war concerns of the country in the context of popular culture development4. Igarashi claims that post-war crisis in the Japanese culture can be identified at different levels and different factors are influencing the process of cultural development in post-war Japan. The author is focused on psychological aspects of nation history development. Identity of historical development can be traced with respect to historical factors. In Barefoot Gen by Keiji Nakazawa (2004), the issues of family difficulties after war are considered. Family members showed their following social norms though they were puzzled by

Saturday, September 7, 2019

Pharmacology (Drug Profile Midazolam) Essay Example | Topics and Well Written Essays - 2750 words

Pharmacology (Drug Profile Midazolam) - Essay Example b) Oral administration is also done for short term treatment. This is done mainly for the insomnia patients. c) Midazolam is also indicted for the management of schizopernia. 3. Midazolam is found to interact with many drugs. The drug interaction is found to either increase the activity or decrease the activity of Midazoalm. The drug interaction occurs mainly with the antipsychotic medications, barbiturates, antibiotics and antifungal, cimetidine, Diltiazem, Narcotics, Seizure and Sleep medications, alcohol and antidepressant medicines such as Antipsychotic drugs include: Aripipraxole , asenapine, chlorpromazine, clozapine, fluphenazine, haloperidol, Iloperidone, loxapine, lurasidone, molindone, olanzapine, paliperidone and perphenazine and pimozide. Barbutarates include: Amobarbital, Butalbital, Pentobarbital and Secobarbital. Antibiotics such as Clarithomycin, Erythromycin, Isoniazid, Itraconazole , ketoconazole and Telithromycin. Narcotics such as morphine and oxycodone are used i n combination with Midazolam. (drugs.emedtv.com) The pharmacokinetic drug interactions are found to occur based on the enzymes involved in the metabolism. The drug interaction with the CNS depressants such as alcohols, opioids and barbiturates are found to have lethal, clinical and forensic consequences with midazolam. Many studies have found that this interaction results in death. (Mozayani and Raymon 2004). Similarly when analgesics are used along with the midazolam, they are found to have greater sedative effects. The gastrointestinal agents when combined with midazolam are found to increase the rate of absorption of the drug. Cimetidine when used along with Midazolam is found to increase the retention time of Midazolam in the body. Similarly the antifungal agents are also found to inhibit the movement of Midazolam from the body. 4. a) The mechanism of interaction of Midozolam is understood well. The main target of Midazolam is the GABAa receptor. This is an ionotropic receptor w ith gamma amino butyric acid as the endogenous ligand. When GABAa receptor is activated then it transmits Chloride ions through their pores and polarizes the neurons. This polarization results in the inhibition of the neurotransmission. The benzodiazepines binds to the receptor found between the alpha and gamma receptor subunits. The five subunits of GABA receptor are sensitive to benzodiazepine. When benzodiazepine binds to the alpha and the gamma subunits of the GABA receptor, and brings the receptor into its control. The binding brings out a change in the conformation of the GABA – alpha and makes them to open the chloride ion channel and this polarizes the membrane. This process inhibits the signal transduction pathway by arresting the GABA molecules and creating sedatory and anxiolytic effects to the human. (Sigel 2002). b. Midozolam is the substrate for the receptor GABA only. This is very specific in nature. It binds to the GABA receptors that are having only alpha and gamma subunits. The binding of benzodiazepine modifies the GABAs response by the receptor. As these receptors are found in the cerebral cortex region, limbic system, cerebellar cortex and spinal cord, its effect can be felt in many parts of the body. The two compartmental model enables the specificity of the molecule and increases the sensitivity. (Stoelting and Miller 2007) c.